Zhang Lin spoke with such clarity that all the doctors present were inspired. Indeed, working at the Institute would surely lead to some accomplishments.

Even someone like Zhang Lin became a specialist; they all thought they could do even better. That was everyone's consensus.

Previously, Zhang Lin and Little Five's reputation at the Hospital wasn't great. As for Little Five, everyone believed he only got into the Institute because he was Yang Ping's protégé from the City People's Hospital. There were countless doctors more skilled than him at Sanbo Hospital.

And Zhang Lin was merely doing menial tasks for Yang Ping initially, thus entering the Institute by association.

These two were seen as having no skills and purely relying on connections. That was their image in everyone's mind back then.

Yet no one anticipated the pioneering days of the Institute, when there was little interest among people to join.

Now, Zhang Lin and Little Five are different; from "Hook Surgery" to solving a challenging problem in genetics, they are genuine experts. Even their manner of speaking has changed—they have the demeanor of specialists.

"While in pediatrics, we conducted genetic tests. The genetic sequencing turned up negative; we didn't find any pathogenic genes," Director Bai personally responded.

Zhang Lin asked, "If no pathogenic genes are found, then we're facing a considerable issue—in the absence of identifying the pathogenic gene loci, targeted medication is impossible, leaving us only to symptomatic treatment."

Targeted treatment refers to addressing specific symptoms, whereas dealing with the root is curative.

"Currently, we are maintaining symptomatic treatment using non-steroidal anti-inflammatory drugs and phosphates, while being cautious about using glucocorticoids and tumor necrosis factor-alpha antagonists, preferring to wait for further discussion," Director Bai communicated prudently.

The genetic tests being negative complicates treatment due to the inability to pinpoint the source for curative intervention.

"The absence of identified pathogenic genes does not imply their non-existence," Zhang Lin said with earnest seriousness, like a seasoned expert reflecting carefully before responding.

The entire room of doctors erupted in surprise; indeed, opinions from the Institute carried a different weight.

"It's entirely possible she carries pathogenic genes that are currently unknown, not present within the human disease gene information database. This dynamic database updates continually, not static, and genetic testing only compares a patient's genes to database info, seeking pathogenic traits via comparison."

This statement caused further astonishment, demonstrating Zhang Lin's perceptive insights far surpassing his peers.

Yang Ping smiled subtly; despite their common qualities, Zhang Lin and Little Five's efforts had not gone unnoticed. Even though they had shortcomings—Little Five's glibness and Zhang Lin's tendency to boast—they shared a steadfast quality, focusing on achievable tasks and those others neglect, staying grounded and diligent, unfazed by scorn or ridicule, courageously pursuing their work.

Even before Professor Yang intervened, Zhang Lin's case discussion regarding Zhezhe had reached new depths.

"I suggest re-analyzing the genetic sequencing report—not simply running through existing diagnostic methods—by reassessing the exome sequencing report, meticulously screening each mutated loci," Zhang Lin held the microphone as he spoke.

"If concerned about the time-consuming manual screening, we can utilize the AI model from Nandu Medical University, which delivers results in seconds."

A voice added in the Meeting Room, leading everyone to turn towards the speaker—Lu Xiaowu, one of the Institute's renowned duo, also speaking with composed authority, fitting for someone trained at the Institute.

Yang Ping nodded slightly; they were correct. Having seen Tong Yongqian's case from beginning to end, Zhang Lin and Little Five had acquired fundamental research knowledge and methodology, capable of understanding the core logic of diagnosis and treatment.

Director Bai and Director Tan both appeared surprised, particularly Director Bai who knew Zhang Lin well, previously a young doctor in Orthopedics, now admirably transformed since joining the Institute.

"I just reviewed the genetic sequencing report, which lacks the complete exome sequencing details. If we truly wish to elucidate the etiology and achieve target-oriented treatment, uncovering the cause is essential—there surely exists a pathogenic gene, but we have yet to locate it, our methods flawed," Little Five stood as he spoke.

If Zhang Lin and Little Five perform surgery, having just one on stage might not convince others of their expertise, but with both together, their skill level unquestionably exceeds that of any teaching tertiary hospital's lead directors.

Zhang Lin's suggestions shed light on the matter, undermining Director Bai's intent for extensive case discussion now pinpointed by Zhang Lin, indicating little necessity for further debate.

Director Tan turned towards Yang Ping, who nodded slightly, confirming, "They are correct; this patient undoubtedly has pathogenic genes, just not uncovered through current standard methods. We can certainly identify these through comprehensive comparative analysis—the gene must exist, likely a novel mutation not yet in the gene database. It's important to realize all gene data entries are manually recorded into the database, which always has inherent delays."

If you find any errors ( broken links, non-standard content, etc.. ), Please let us know < report chapter > so we can fix it as soon as possible.